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MSH6 Antikörper (AA 357-388)

Der Kaninchen Polyklonal anti-MSH6 Antikörper (ABIN7874275) detektiert spezifisch MSH6 in WB, IF, ELISA und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.
Produktnummer ABIN7874275
644,88 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μg
Lieferung nach: Deutschland
Lieferung in 6 bis 9 Werktagen

Kurzübersicht für MSH6 Antikörper (AA 357-388) (ABIN7874275)

Target

Alle MSH6 Antikörper anzeigen
MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

Reaktivität

  • 207
  • 58
  • 53
  • 8
  • 6
  • 2
  • 2
  • 1
  • 1
  • 1
Human

Wirt

  • 118
  • 86
  • 3
Kaninchen

Klonalität

  • 157
  • 49
  • 1
Polyklonal

Konjugat

  • 124
  • 10
  • 5
  • 5
  • 5
  • 5
  • 5
  • 5
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MSH6 Antikörper ist unkonjugiert

Applikation

  • 140
  • 103
  • 80
  • 48
  • 48
  • 32
  • 28
  • 19
  • 14
  • 13
  • 8
  • 4
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), ELISA, Flow Cytometry (FACS)
  • Bindungsspezifität

    • 68
    • 15
    • 14
    • 8
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 357-388

    Verwendungszweck

    MSH6 Antibody

    Aufreinigung

    Antigen affinity purified

    Immunogen

    Recombinant human protein (amino acids D357-H388) was used as the immunogen for the MSH6 antibody.

    Isotyp

    IgG
  • Applikationshinweise

    Optimal dilution of the MSH6 antibody should be determined by the researcher.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Lyophilized

    Buffer

    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

    Lagerung

    4 °C,-20 °C

    Informationen zur Lagerung

    After reconstitution, the MSH6 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
  • Target

    MSH6 (MutS Homolog 6 (E. Coli) (MSH6))

    Andere Bezeichnung

    MSH6

    Hintergrund

    MSH6 or mutS homolog 6 is a gene that codes for DNA mismatch repair protein Msh6 in the budding yeast Saccharomyces cerevisiae. This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.

    UniProt

    P52701

    Pathways

    DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
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