MYCN Antikörper (AA 335-463)

Produktnummer ABIN7874045

Dieser Maus Monoklonal Antikörper detektiert spezifisch MYCN in ELISA und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für MYCN Antikörper (AA 335-463) (ABIN7874045)

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MYCN Antikörper ist unkonjugiert

Applikation: ELISA, Flow Cytometry (FACS)

Güteklasse: Carrier-free

Klon: PCRP-MYCN-1A9

Produktdetails anti-MYCN Antikörper

Bindungsspezifität: AA 335-463

Verwendungszweck: MYCN Antibody / n-Myc (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant human MYCN protein (within amino acids 335-463) was used as the immunogen for the MYCN antibody.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MYCN antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the MYCN antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu MYCN

Target: MYCN (N-Myc Proto-Oncogene Protein (MYCN))

Andere Bezeichnung: MYCN

Hintergrund: The v-Myc oncogene, initially identified in the MC29 avian retrovirus, causes myelocytomas, carcinomas, sarcomas and lymphomas, and belongs to a family of oncogenes conserved throughout evolution. In humans, the family consists of five genes: c-Myc, N-Myc, R-Myc, L-Myc and B-Myc. Amplification of the N-Myc gene has been found in human neuroblastomas and cell lines. Its amplification correlates well with the stage of neuroblastoma disease. Immunological studies have shown that the human N-Myc gene encodes a nuclear phosphoprotein that exhibits relatively short (30 min) half life in vivo. The prototype member of the family, c-Myc p67, binds DNA in a sequence-specific manner subsequent to dimerization with a second basic region helix-loop-helix leucine zipper motif protein, designated Max.

UniProt: P04198