Poliovirus Receptor Antikörper (AA 28-417)

Produktnummer ABIN7873266

Der Kaninchen Polyklonal anti-Poliovirus Receptor Antikörper wird verwendet zum Nachweis von Poliovirus Receptor in Proben von Human. Er wurde validiert für WB, ELISA, IF und IHC (p).

Kurzübersicht für Poliovirus Receptor Antikörper (AA 28-417) (ABIN7873266)

Target: Poliovirus Receptor (PVR)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Poliovirus Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Poliovirus Receptor Antikörper

Bindungsspezifität: AA 28-417

Verwendungszweck: CD155 Antibody / Poliovirus Receptor / PVR

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids D28-R417) was used as the immunogen for the CD155 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the CD155 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the CD155 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Andere Bezeichnung: CD155

Hintergrund: CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: P15151

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interaktom