Rubicon Antikörper (AA 241-271)
Kurzübersicht für Rubicon Antikörper (AA 241-271) (ABIN7872730)
Target
Alle Rubicon (KIAA0226) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 241-271
-
Verwendungszweck
- Rubicon Antibody / RUBCN / BARON
-
Aufreinigung
- Antigen affinity purified
-
Immunogen
- A portion of amino acids 241-271 from the human protein was used as the immunogen for the Rubicon antibody.
-
Isotyp
- Ig Fraction
-
-
-
-
Applikationshinweise
- The stated application concentrations are suggested starting points. Titration of the Rubicon antibody may be required due to differences in protocols and secondary/substrate sensitivity.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Aliquot the Rubicon antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
-
- Rubicon (KIAA0226) (KIAA0226)
-
Andere Bezeichnung
- Rubicon
-
Hintergrund
- Inhibits PIK3C3 activity, under basal conditions negatively regulates PI3K complex II (PI3KC3-C2) function in autophagy. Negatively regulates endosome maturation and degradative endocytic trafficking and impairs autophagosome maturation process. Can sequester UVRAG from association with a class C Vps complex (possibly the HOPS complex) and negatively regulates Rab7 activation. [UniProt]
-
UniProt
- Q92622
-
Pathways
- Autophagie
Target
-