Rubicon Antikörper (AA 859-972)
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- Target Alle Rubicon (KIAA0226) Antikörper anzeigen
- Rubicon (KIAA0226) (KIAA0226)
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Bindungsspezifität
- AA 859-972
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser Rubicon Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human RUBCN (AA: 859-972) expressed in E. coli.
- Klon
- 4F5B5
- Isotyp
- IgG1
- Top Product
- Discover our top product KIAA0226 Primärantikörper
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- Applikationshinweise
- WB:1:500 - 1:2000, ELISA:1:10000,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Buffer
- Purified antibody in PBS with 0.05 % sodium azide
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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- Target
- Rubicon (KIAA0226) (KIAA0226)
- Andere Bezeichnung
- RUBCN (KIAA0226 Produkte)
- Synonyme
- RUBICON antikoerper, 5330403K09 antikoerper, Kiaa0226 antikoerper, Rubicon antikoerper, mKIAA0226 antikoerper, RUN and cysteine rich domain containing beclin 1 interacting protein antikoerper, KIAA0226 antikoerper, RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein antikoerper, RUBCN antikoerper, KIAA0226 antikoerper, Rubcn antikoerper
- Hintergrund
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Description: The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Aliases: SCAR15, RUBICON, KIAA0226
- Molekulargewicht
- 108.6 kDa
- Gen-ID
- 9711
- Pathways
- Autophagie
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