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Rubicon Antikörper (AA 859-972)

KIAA0226 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 4F5B5 unconjugated
Produktnummer ABIN7193445
  • Target Alle Rubicon (KIAA0226) Antikörper anzeigen
    Rubicon (KIAA0226) (KIAA0226)
    Bindungsspezifität
    • 18
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 859-972
    Reaktivität
    • 33
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 32
    • 1
    Maus
    Klonalität
    • 32
    • 1
    Monoklonal
    Konjugat
    • 16
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser Rubicon Antikörper ist unkonjugiert
    Applikation
    • 29
    • 19
    • 14
    • 13
    • 10
    • 9
    • 5
    • 3
    Western Blotting (WB), ELISA
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human RUBCN (AA: 859-972) expressed in E. coli.
    Klon
    4F5B5
    Isotyp
    IgG1
    Top Product
    Discover our top product KIAA0226 Primärantikörper
  • Applikationshinweise
    WB:1:500 - 1:2000, ELISA:1:10000,
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    Rubicon (KIAA0226) (KIAA0226)
    Andere Bezeichnung
    RUBCN (KIAA0226 Produkte)
    Synonyme
    RUBICON antikoerper, 5330403K09 antikoerper, Kiaa0226 antikoerper, Rubicon antikoerper, mKIAA0226 antikoerper, RUN and cysteine rich domain containing beclin 1 interacting protein antikoerper, KIAA0226 antikoerper, RUN domain and cysteine-rich domain containing, Beclin 1-interacting protein antikoerper, RUBCN antikoerper, KIAA0226 antikoerper, Rubcn antikoerper
    Hintergrund

    Description: The protein encoded by this gene is a negative regulator of autophagy and endocytic trafficking and controls endosome maturation. This protein contains two conserved domains, an N-terminal RUN domain and a C-terminal DUF4206 domain. The RUN domain is involved in Ras-like GTPase signaling, and the DUF4206 domain contains a diacylglycerol (DAG) binding-like motif. Mutation in this gene results in deletion of the DAG binding-like motif and causes a recessive ataxia. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

    Aliases: SCAR15, RUBICON, KIAA0226

    Molekulargewicht
    108.6 kDa
    Gen-ID
    9711
    Pathways
    Autophagie
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