Poliovirus Receptor Antikörper (AA 24-345)

Produktnummer ABIN7872685

Der Kaninchen Polyklonal anti-Poliovirus Receptor Antikörper (ABIN7872685) detektiert spezifisch Poliovirus Receptor in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Maus und Ratte.

Kurzübersicht für Poliovirus Receptor Antikörper (AA 24-345) (ABIN7872685)

Target: Poliovirus Receptor (PVR)

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Poliovirus Receptor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Poliovirus Receptor Antikörper

Bindungsspezifität: AA 24-345

Verwendungszweck: Pvr Antibody / Poliovirus receptor / Cd155

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant mouse protein (amino acids R24-R345) was used as the immunogen for the Pvr antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Pvr antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Pvr antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Poliovirus Receptor

Target: Poliovirus Receptor (PVR)

Andere Bezeichnung: Pvr

Hintergrund: CD155 (cluster of differentiation 155) also known as the poliovirus receptor is a protein that in humans is encoded by the PVR gene. The protein encoded by this gene is a transmembrane glycoprotein belonging to the immunoglobulin superfamily. The external domain mediates cell attachment to the extracellular matrix molecule vitronectin, while its intracellular domain interacts with the dynein light chain Tctex-1/DYNLT1. The gene is specific to the primate lineage, and serves as a cellular receptor for poliovirus in the first step of poliovirus replication. Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q91WP1

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Cancer Immune Checkpoints, SARS-CoV-2 Protein Interaktom