STS Antikörper (AA 24-193)

Produktnummer ABIN7872671

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch STS in WB, ELISA, FACS und IF. Es zeigt Reaktivität gegenüber Proben von Maus.

Kurzübersicht für STS Antikörper (AA 24-193) (ABIN7872671)

Target: STS (Steroid Sulfatase (STS))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)

Produktdetails anti-STS Antikörper

Bindungsspezifität: AA 24-193

Verwendungszweck: Asc Antibody / Pycard / Tms1

Aufreinigung: Antigen affinity purified

Immunogen: E. coli-derived recombinant mouse protein (amino acids K24-S193) was used as the immunogen for the Asc antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Asc antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Asc antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu STS

Target: STS (Steroid Sulfatase (STS))

Andere Bezeichnung: Asc

Hintergrund: PYCARD, often referred to as ASC (Apoptosis-associated speck-like protein containing a CARD), is a protein that in humans is encoded by the PYCARD gene. This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm, however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9EPB4

Pathways: Steroid Hormone Biosynthesis, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation