STS Antikörper (N-Term)

Produktnummer ABIN2745512

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch STS in WB, IHC, FACS, IF, ICC, IP und Func. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für STS Antikörper (N-Term) (ABIN2745512)

Target: STS (Steroid Sulfatase (STS))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP), Functional Studies (Func)

Produktdetails anti-STS Antikörper

Bindungsspezifität: N-Term

Verwendungszweck: anti-Asc, pAb (AL177) (preservative free)

Spezifität: Recognizes human and mouse Asc.

Produktmerkmale: Polyclonal Antibody. Recognizes human and mouse Asc. Source: Rabbit. Applications: FUNC, ICC, IHC, IP, WB. Liquid. In PBS containing 10 % glycerol. Asc promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. It is a component of the inflammasome, a protein complex which also includes NLRP3/NALP3, CARD8 and CASP1 and whose function is the activation of proinflammatory caspases.

Immunogen: Synthetic peptide corresponding to aa at the N-terminal human Asc.

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: In PBS.

Konservierungsmittel: Without preservative

Handhabung: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Haltbarkeit: 12 months

Details zu STS

Target: STS (Steroid Sulfatase (STS))

Andere Bezeichnung: Asc

Hintergrund:

Alternate Names/Synonyms: Pycard, Target of Methylation-induced Silencing 1, TMS1, Caspase Recruitment Domain-containing Protein 5, Apoptosis-associated Speck-like Protein Containing CARD, CARD5

Product Description: Asc promotes caspase-mediated apoptosis. This proapoptotic activity is mediated predominantly through the activation of caspase-9. It is a component of the inflammasome, a protein complex which also includes NLRP3/NALP3, CARD8 and CASP1 and whose function is the activation of proinflammatory caspases.

UniProt: Q9ULZ3

Pathways: Steroid Hormone Biosynthesis, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation