ICOSLG Antikörper (AA 23-149)

Produktnummer ABIN7872488

Dieser Maus Monoklonal Antikörper detektiert spezifisch ICOSLG in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ICOSLG Antikörper (AA 23-149) (ABIN7872488)

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ICOSLG Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: ISLG-1

Produktdetails anti-ICOSLG Antikörper

Bindungsspezifität: AA 23-149

Verwendungszweck: ICOS Ligand Antibody / ICOS-L / B7RP-1

Aufreinigung: Protein G affinity chromatography

Immunogen: A recombinant fragment of human ICOSLG / B7RP-1 protein within amino acids 23-149 was used as the immunogen for the ICOS Ligand antibody.

Isotyp: IgG1, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ICOS Ligand antibody should be determined by the researcher.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide, *For IHC use only*

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the ICOS Ligand antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu ICOSLG

Target: ICOSLG (Inducible T-Cell Co-Stimulator Ligand (ICOSLG))

Andere Bezeichnung: ICOS Ligand

Hintergrund: Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion, induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function (By similarity). [UniProt]

UniProt: O75144

Pathways: Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation