MLF1 Antikörper (AA 215-244)

Produktnummer ABIN7872230

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MLF1 in WB, FACS und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für MLF1 Antikörper (AA 215-244) (ABIN7872230)

Target: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-MLF1 Antikörper

Bindungsspezifität: AA 215-244

Verwendungszweck: MLF1 Antibody / Myeloid leukemia factor 1

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 215-244 from the human protein was used as the immunogen for the MLF1 antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the MLF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the MLF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu MLF1

Target: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Andere Bezeichnung: MLF1

Hintergrund: MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

UniProt: P58340