MLF1 Antikörper (C-Term)

Produktnummer ABIN652233

Produktdetails anti-MLF1 Antikörper

Target: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Bindungsspezifität: AA 215-244, C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This MLF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 215-244 amino acids from the C-terminal region of human MLF1.

Klon: RB18643

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Haltbarkeit: 6 months

Details zu MLF1

Target: MLF1 (Myeloid Leukemia Factor 1 (MLF1))

Andere Bezeichnung: MLF1 (MLF1 Produkte)

Synonyme: MLF1 antikoerper, HLS7 antikoerper, myeloid leukemia factor 1 antikoerper, myeloid leukemia factor 1 L homeolog antikoerper, MLF1 antikoerper, mlf1.L antikoerper, mlf1 antikoerper, Mlf1 antikoerper

Hintergrund: MLF1 is involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. The protein interferes with erythopoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. It suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. It binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.

Molekulargewicht: 30627

Gen-ID: 4291

NCBI Accession: NP_001123628, NP_001123629, NP_001182361, NP_001182362, NP_001182363, NP_071888

UniProt: P58340