MLF1 Antikörper
Kurzübersicht für MLF1 Antikörper (ABIN7074712)
Target
Alle MLF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Kreuzreaktivität
- Ratte
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant protein corresponding to Mouse Myeloid leukemia factor 1
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Applikationshinweise
- WB (M,R) 1:500-1:1000, IHC/IF (M,R) 1:1000-1:3000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS, pH 7.4, 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- MLF1 (Myeloid Leukemia Factor 1 (MLF1))
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Andere Bezeichnung
- Myeloid leukemia factor 1
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Hintergrund
- Involved in lineage commitment of primary hemopoietic progenitors by restricting erythroid formation and enhancing myeloid formation. Interferes with erythropoietin-induced erythroid terminal differentiation by preventing cells from exiting the cell cycle through suppression of CDKN1B/p27Kip1 levels. Suppresses RFWD2/COP1 activity via CSN3 which activates p53 and induces cell cycle arrest. Binds DNA and affects the expression of a number of genes so may function as a transcription factor in the nucleus.
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Molekulargewicht
- 31 kDa
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Gen-ID
- 17349
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NCBI Accession
- NP_034931
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UniProt
- Q9QWV4
Target
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