PDIA6 Antikörper (AA 20-440)

Produktnummer ABIN7871874

Der Kaninchen Polyklonal anti-PDIA6 Antikörper wird verwendet zum Nachweis von PDIA6 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, FACS, IF, ELISA und IHC (p).

Kurzübersicht für PDIA6 Antikörper (AA 20-440) (ABIN7871874)

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDIA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-PDIA6 Antikörper

Bindungsspezifität: AA 20-440

Verwendungszweck: ERp5 Antibody / Endoplasmic reticulum protein 5 / PDIA6

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids L20-L440) was used as the immunogen for the ERp5 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the ERp5 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the ERp5 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu PDIA6

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Andere Bezeichnung: ERp5

Hintergrund: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, two catalytically active thioredoxin (TRX) domains, a TRX-like domain, and a C-terminal ER-retention sequence. This protein inhibits the aggregation of misfolded proteins and exhibits both isomerase and chaperone activity. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q15084

Pathways: ER-Nucleus Signaling, Cell RedoxHomeostasis