PDIA6 Antikörper (C-Term)

Produktnummer ABIN6264114

Produktdetails anti-PDIA6 Antikörper

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDIA6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Spezifität: PDIA6 Antibody detects endogenous levels of total PDIA6.

Homologie: Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus

Aufreinigung: The antiserum was purified by peptide affinity chromatography using SulfoLink^TM Coupling Resin (Thermo Fisher Scientific).

Immunogen: A synthesized peptide derived from human PDIA6, corresponding to a region within C-terminal amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20 °C. Stable for 12 months from date of receipt.

Haltbarkeit: 12 months

Details zu PDIA6

Target: PDIA6 (Protein Disulfide Isomerase Family A, Member 6 (PDIA6))

Andere Bezeichnung: PDIA6 (PDIA6 Produkte)

Synonyme: 1700015E05Rik antikoerper, AL023058 antikoerper, C77895 antikoerper, CaBP5 antikoerper, P5 antikoerper, Txndc7 antikoerper, ERP5 antikoerper, TXNDC7 antikoerper, CaBP1 antikoerper, pdi-p5 antikoerper, erp5 antikoerper, pdia6 antikoerper, pdip5 antikoerper, txndc7 antikoerper, protein disulfide isomerase family A member 6 antikoerper, protein disulfide isomerase associated 6 antikoerper, protein disulfide isomerase family A, member 6 antikoerper, protein disulfide isomerase family A member 6 L homeolog antikoerper, PDIA6 antikoerper, Pdia6 antikoerper, pdia6.L antikoerper

Hintergrund:

Description: May function as a chaperone that inhibits aggregation of misfolded proteins (PubMed:12204115). Negatively regulates the unfolded protein response (UPR) through binding to UPR sensors such as ERN1, which in turn inactivates ERN1 signaling (PubMed:24508390). May also regulate the UPR via the EIF2AK3 UPR sensor (PubMed:24508390). Plays a role in platelet aggregation and activation by agonists such as convulxin, collagen and thrombin (PubMed:15466936).

Gene: PDIA6

Molekulargewicht: 54 kDa

Gen-ID: 10130

UniProt: Q15084

Pathways: ER-Nucleus Signaling, Cell RedoxHomeostasis