TCL1A Antikörper (AA 2-109)

Produktnummer ABIN7871766

Der Maus Monoklonal anti-TCL1A Antikörper wird verwendet zum Nachweis von TCL1A in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für TCL1A Antikörper (AA 2-109) (ABIN7871766)

Target: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TCL1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: TCL1-2079

Produktdetails anti-TCL1A Antikörper

Bindungsspezifität: AA 2-109

Verwendungszweck: TCL1 Antibody (azide and preservative free)

Aufreinigung: Protein G affinity chromatography

Immunogen: A portion of amino acids 2-109 from the human protein was used as the immunogen for the TCL1 antibody.

Isotyp: IgG2a, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the TCL1 antibody should be determined by the researcher.

1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the TCL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu TCL1A

Target: TCL1A (T-Cell Leukemia/lymphoma 1A (TCL1A))

Andere Bezeichnung: TCL1

Hintergrund: T-cell leukemia/Lymphoma Protein 1A (TCL-1A), also known as p14TCL1 is a product of the TCL1 gene that is involved in T-cell prolymphocytic leukemia (TPLL). T-PLL is a rare form of mature T-cell leukemia, which is consistently associated with chromosomal rearrangements characterized by the juxtaposition of the TCRA locus on chromosome 14q11 and the TCL1A gene on 14q32.13. TCL1 is overexpressed in Burkitt lymphoma, the majority of AIDS-related non-Hodgkin lymphoma-designated immunoblastic plasmacytoid lymphoma, lymphoblastic lymphoma, chronic lymphocytic leukemia, mantle cell lymphoma, follicular lymphoma, diffuse large B-cell lymphoma, and primary cutaneous B-cell lymphoma.

UniProt: P56279

Pathways: Stem Cell Maintenance