MYBL1 Antikörper (AA 199-752)

Produktnummer ABIN7871757

Der Kaninchen Polyklonal anti-MYBL1 Antikörper wird verwendet zum Nachweis von MYBL1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für MYBL1 Antikörper (AA 199-752) (ABIN7871757)

Target: MYBL1 (Myb-Like Protein 1 (MYBL1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MYBL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-MYBL1 Antikörper

Bindungsspezifität: AA 199-752

Verwendungszweck: Myb-related protein A Antibody / A-Myb / MYBL1

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids K199-L752) was used as the immunogen for the Myb-related protein A antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Myb-related protein A antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Myb-related protein A antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu MYBL1

Target: MYBL1 (Myb-Like Protein 1 (MYBL1))

Andere Bezeichnung: Myb-related protein A

Hintergrund: Myb-related protein A is a protein that in humans is encoded by the MYBL1 gene. A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t(14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.

UniProt: P10243

Pathways: Zellzyklus, Chromatin Binding