MUTYH Antikörper (AA 187-528)

Produktnummer ABIN7871513

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MUTYH in WB, ELISA und FACS. Es zeigt Reaktivität gegenüber Proben von Human und Ratte.

Kurzübersicht für MUTYH Antikörper (AA 187-528) (ABIN7871513)

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MUTYH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-MUTYH Antikörper

Bindungsspezifität: AA 187-528

Verwendungszweck: MUTYH Antibody / Adenine DNA glycosylase / MYH1

Aufreinigung: Antigen affinity purified

Immunogen: An E.coli-derived human recombinant protein (amino acids A187-N528) was used as the immunogen for the MUTYH antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the MUTYH antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the MUTYH antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu MUTYH

Target: MUTYH (MutY Homolog (E. Coli) (MUTYH))

Andere Bezeichnung: MUTYH

Hintergrund: This gene encodes a DNA glycosylase involved in oxidative DNA damage repair. The enzyme excises adenine bases from the DNA backbone at sites where adenine is inappropriately paired with guanine, cytosine, or 8-oxo-7,8-dihydroguanine, a major oxidatively damaged DNA lesion. The protein is localized to the nucleus and mitochondria. This gene product is thought to play a role in signaling apoptosis by the introduction of single-strand breaks following oxidative damage. Mutations in this gene result in heritable predisposition to colorectal cancer, termed MUTYH-associated polyposis (MAP). Multiple transcript variants encoding different isoforms have been found for this gene.

UniProt: Q9UIF7

Pathways: DNA Reparatur