Tec Protein Tyrosine Kinase (TEC) (AA 175-205) Antikörper

Produktnummer ABIN7871303

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Tec Protein Tyrosine Kinase in WB, IF und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Tec Protein Tyrosine Kinase (TEC) (AA 175-205) Antikörper (ABIN7871303)

Target: Tec Protein Tyrosine Kinase (TEC)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails

Bindungsspezifität: AA 175-205

Verwendungszweck: TEC Antibody

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 175-205 from the human protein was used as the immunogen for the TEC antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the TEC antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the TEC antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Antigendetails

Target: Tec Protein Tyrosine Kinase (TEC)

Andere Bezeichnung: TEC

Hintergrund: TEC belongs to the TEC subfamily of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. TEC family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. TEC kinase is an integral component of T cell signaling and has a distinct role in T cell activation. TEC may be associated with myelodysplastic syndrome.

UniProt: P42680

Pathways: Fc-epsilon Rezeptor Signalübertragung