Tec Protein Tyrosine Kinase (TEC) Antikörper

Produktnummer ABIN969434

Es sind 4+ Publikationen für dieses Produkt verfügbar. Der Maus Monoklonal anti-Tec Protein Tyrosine Kinase Antikörper wird verwendet zum Nachweis von Tec Protein Tyrosine Kinase in Proben von Human. Er wurde validiert für ELISA.

Kurzübersicht für Tec Protein Tyrosine Kinase (TEC) Antikörper (ABIN969434)

Target: Tec Protein Tyrosine Kinase (TEC)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: ELISA

Klon: 3A5

Produktdetails

Verwendungszweck: TEC Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of TEC expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen

Jolkver, Emer, Ballan, Krämer, Eikmanns, Marin: "Identification and characterization of a bacterial transport system for the uptake of pyruvate, propionate, and acetate in Corynebacterium glutamicum." in: Journal of bacteriology, Vol. 191, Issue 3, pp. 940-8, (2009) (PubMed).

van Dijk, van Den Akker, Amelsvoort, Mano, Löwenberg, von Lindern: "Stem cell factor induces phosphatidylinositol 3'-kinase-dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells." in: Blood, Vol. 96, Issue 10, pp. 3406-13, (2000) (PubMed).

Tsai, Chow, Chen, Huang, Hong, Jan, Kuo, Tsao, Chen, Cheng: "Cef1p is a component of the Prp19p-associated complex and essential for pre-mRNA splicing." in: The Journal of biological chemistry, Vol. 274, Issue 14, pp. 9455-62, (1999) (PubMed).

Kitanaka, Mano, Conley, Campana: "Expression and activation of the nonreceptor tyrosine kinase Tec in human B cells." in: Blood, Vol. 91, Issue 3, pp. 940-8, (1998) (PubMed).

Antigendetails

Target: Tec Protein Tyrosine Kinase (TEC)

Andere Bezeichnung: TEC

Hintergrund: TEC, it belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.

Molekulargewicht: 74 kDa

UniProt: P42680

Pathways: Fc-epsilon Rezeptor Signalübertragung