GZMB Antikörper (AA 175-203)
Kurzübersicht für GZMB Antikörper (AA 175-203) (ABIN7871301)
Target
Alle GZMB Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 175-203
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Verwendungszweck
- GZMB Antibody / Granzyme B
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Aufreinigung
- Purified
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Immunogen
- A portion of amino acids 175-203 from the human protein was used as the immunogen for the GZMB antibody.
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Isotyp
- Ig Fraction
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Applikationshinweise
- The stated application concentrations are suggested starting points. Titration of the GZMB antibody may be required due to differences in protocols and secondary/substrate sensitivity.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- In 1X PBS, pH 7.4, with 0.09 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the GZMB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- GZMB (Granzyme B (GZMB))
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Andere Bezeichnung
- GZMB
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Hintergrund
- Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response.
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UniProt
- P10144
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Pathways
- Apoptose, Caspase Kaskade in der Apoptose
Target
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