DCK Antikörper (AA 171-200)

Produktnummer ABIN7871260

Der Kaninchen Polyklonal anti-DCK Antikörper (ABIN7871260) detektiert spezifisch DCK in WB, IF und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für DCK Antikörper (AA 171-200) (ABIN7871260)

Target: DCK (Deoxycytidine Kinase (DCK))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DCK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DCK Antikörper

Bindungsspezifität: AA 171-200

Verwendungszweck: Deoxycytidine kinase Antibody / DCK

Aufreinigung: Purified

Immunogen: A portion of amino acids 171-200 from the human protein was used as the immunogen for the Deoxycytidine kinase antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the Deoxycytidine kinase antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Deoxycytidine kinase antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu DCK

Target: DCK (Deoxycytidine Kinase (DCK))

Andere Bezeichnung: Deoxycytidine kinase

Hintergrund: Deoxycytidine kinase is responsible for the phosphorylation of several deoxyribonucleosides and their analogs. Deficiency of this enzyme activity is associated with resistance to antiviral and anticancer chemotherapeutic agents, whereas increased enzyme activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. It is the rate limiting enzyme in the activation of many important anticancer and retroviral drugs and its activity is often decreased in cells that are resistant to cytosine arabinoside.

UniProt: P27707