Hexokinase 1 Antikörper (AA 17-323)

Produktnummer ABIN7871223

Der Maus Monoklonal anti-Hexokinase 1 Antikörper wird verwendet zum Nachweis von Hexokinase 1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IF, IHC (p), FACS und IHC (fro).

Kurzübersicht für Hexokinase 1 Antikörper (AA 17-323) (ABIN7871223)

Target: Hexokinase 1 (HK1)

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Hexokinase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Klon: 2I4

Produktdetails anti-Hexokinase 1 Antikörper

Bindungsspezifität: AA 17-323

Verwendungszweck: HK1 Antibody / Hexokinase 1

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids D17-R323) was used as the immunogen for the HK1 antibody.

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the HK1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the HK1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu Hexokinase 1

Target: Hexokinase 1 (HK1)

Andere Bezeichnung: HK1

Hintergrund: Hexokinase-1 (HK1) is an enzyme that in humans is encoded by the HK1 gene on chromosome 10. It is mapped to 10q22.1. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in several transcript variants which encode different isoforms, some of which are tissue-specific.

UniProt: P19367

Pathways: Carbohydrate Homeostasis, Warburg Effekt