RYK Antikörper (AA 160-190)

Produktnummer ABIN7871095

Der Kaninchen Polyklonal anti-RYK Antikörper (ABIN7871095) detektiert spezifisch RYK in WB und IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für RYK Antikörper (AA 160-190) (ABIN7871095)

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RYK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-RYK Antikörper

Bindungsspezifität: AA 160-190

Verwendungszweck: RYK Antibody

Aufreinigung: Antigen affinity purified

Immunogen: A portion of amino acids 160-190 from the human protein were used as the immunogen for the RYK antibody.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: The stated application concentrations are suggested starting points. Titration of the RYK antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the RYK antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu RYK

Target: RYK (RYK Receptor-Like Tyrosine Kinase (RYK))

Andere Bezeichnung: RYK

Hintergrund: RYK is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. A nine nucleotide insertion in some transcripts results in the SLG variant. It is not established whether this is a product of alternative splicing or a second gene, since evidence for a second gene or pseudogene on chromosome 17 exists.

UniProt: P34925

Pathways: RTK Signalweg, WNT Signalweg, Regulation of Cell Size