Rekombinanter Prostate Specific Antigen Antikörper (AA 150-250)

Produktnummer ABIN7870868

Dieser Kaninchen Monoklonal Antikörper detektiert spezifisch Prostate Specific Antigen in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Rekombinanter Prostate Specific Antigen Antikörper (AA 150-250) (ABIN7870868)

Target: Prostate Specific Antigen (PSA)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Prostate Specific Antigen Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: KLK3-7128R

Produktdetails anti-Prostate Specific Antigen Antikörper

Bindungsspezifität: AA 150-250

Verwendungszweck: Recombinant Prostate Specific Antigen Antibody / PSA (azide and preservative free)

Aufreinigung: Protein A/G affinity

Immunogen: A portion of amino acids 150-250 was used as the immunogen for the recombinant Prostate Specific Antigen antibody.

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the recombinant Prostate Specific Antigen antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the recombinant Prostate Specific Antigen antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu Prostate Specific Antigen

Target: Prostate Specific Antigen (PSA)

Andere Bezeichnung: Prostate Specific Antigen

Hintergrund: Prostate-specific antigen (PSA) is a single-chain glycoprotein of 237 amino acids containing approximately 8 % carbohydrate. It is a serine protease produced almost exclusively by prostatic epithelial cells.Immunohistochemically PSA is expressed in the highly specialized apically-superficial layer of female and male secretory cells of the prostate gland, and is readily demonstrated in adenocarcinomas of the prostate in about 99 % of the cases. There is a correlation between malignancy grade and intensity of staining, high grade carcinomas displaying weaker expression. About 1 % of poorly differentiated carcinomas have been negative for PSA.Due to the high specificity of PSA for prostatic glandular epithelium, it is very useful in identifying prostatic carcinoma in the prostate and in the adjacent organs often affected by epithelial malignancies, i.e. rectum and urinary bladder. PSA may be used in a panel together with NKX3.1 and Prostein, which are at least as sensitive and slightly more specific than PSA.

UniProt: P07288

Pathways: Komplementsystem