POU2AF1 Antikörper (AA 148-255)

Produktnummer ABIN7870761

Der Maus Monoklonal anti-POU2AF1 Antikörper wird verwendet zum Nachweis von POU2AF1 in Proben von Human. Er wurde validiert für IHC (p).

Kurzübersicht für POU2AF1 Antikörper (AA 148-255) (ABIN7870761)

Target: POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser POU2AF1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: BOB1-2423

Produktdetails anti-POU2AF1 Antikörper

Bindungsspezifität: AA 148-255

Verwendungszweck: BOB1 Antibody (azide and preservative free)

Aufreinigung: Protein G affinity

Immunogen: A portion of amino acids 148-255 from the human protein was used as the immunogen for the BOB1 antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the BOB1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store the BOB1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Details zu POU2AF1

Target: POU2AF1 (POU Class 2 Associating Factor 1 (POU2AF1))

Andere Bezeichnung: BOB1

Hintergrund: BOB1, also called POU2AF1, expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB1. Conversely, only some cases of classical Hodgkin lymphoma show BOB1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity.

UniProt: Q16633