This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This POU2AF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-27 amino acids from the N-terminal region of human POU2AF1.
BOB1 antikoerper, OBF-1 antikoerper, OBF1 antikoerper, OCAB antikoerper, BOB-1 antikoerper, BOB.1 antikoerper, Bob-1 antikoerper, Bob1 antikoerper, OBF.1 antikoerper, OCA-B antikoerper, POU class 2 associating factor 1 antikoerper, POU domain, class 2, associating factor 1 antikoerper, POU2AF1 antikoerper, Pou2af1 antikoerper
Hintergrund
POU2AF1 is transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.