POU2AF1
Reaktivität: Human
WB, FACS
Wirt: Maus
Monoclonal
24GB13345
unconjugated
Applikationshinweise
Optimal dilution of the BOB-1 antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
1 mg/mL in 1X PBS, BSA free, sodium azide free
Konservierungsmittel
Azide free
Lagerung
-20 °C
Informationen zur Lagerung
Aliquot the BOB-1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
Target
POU2AF1
(POU Class 2 Associating Factor 1 (POU2AF1))
Andere Bezeichnung
BOB-1
Hintergrund
BOB.1 expression in a variety of established B-cell lines, representing different stages of B-cell development, has suggested a constitutive, B-cell-specific expression pattern. LP cells in nodular lymphocyte predominant Hodgkin lymphoma, because they are germinal center-derived, are consistently immuno-positive for BOB.1. Conversely, only some cases of classical Hodgkin lymphoma show BOB.1 immuno-reactivity within the Hodgkin and Reed-Sternberg cells. Expression of BOB.1 has been reported in follicular center cell lymphoma, diffuse large B-cell lymphoma and some cases of acute myeloid leukemia. B-CLL, marginal zone lymphoma, and mantle cell lymphoma may show weak to moderate immunoreactivity.