Rekombinanter Topoisomerase II alpha Antikörper (AA 1431-1531)
Kurzübersicht für Rekombinanter Topoisomerase II alpha Antikörper (AA 1431-1531) (ABIN7870710)
Target
Alle Topoisomerase II alpha (TOP2A) Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
Klon
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Bindungsspezifität
- AA 1431-1531
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Verwendungszweck
- Topoisomerase II alpha Antibody / TOP2A (azide and preservative free)
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A recombinant partial protein sequence (within amino acids 1431-1531) from the human protein was used as the immunogen for the Topoisomerase II alpha antibody.
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Isotyp
- IgG, kappa
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anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1435-1531) antibody
TOP2A Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 1E2 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) antibodyTOP2A Reaktivität: Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1352-1493) antibodyTOP2A Reaktivität: Human, Maus WB, IHC, IF Wirt: Maus Monoclonal TOP2A-1361 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1100-1530) antibodyTOP2A Reaktivität: Human, Ratte WB, ELISA, FACS, ICC Wirt: Maus Monoclonal 6C12G12 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) antibodyKD Validated TOP2A Reaktivität: Human WB, FACS, IF (p) Wirt: Kaninchen Monoclonal 24GB1915 unconjugated Recombinant Antibody
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1100-1530) antibodyTOP2A Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 6D4B2 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (Internal Region) antibodyTOP2A Reaktivität: Human, Maus WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1167-1196), (C-Term) antibodyTOP2A Reaktivität: Human WB, IF, IHC (p) Wirt: Kaninchen Polyclonal RB24346 unconjugated
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (AA 1352-1493) antibodyTOP2A Reaktivität: Human IHC Wirt: Kaninchen Monoclonal 802R unconjugated Recombinant Antibody
anti-Topoisomerase (DNA) II alpha 170kDa (TOP2A) (C-Term) antibodyTOP2A Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal dilution of the Topoisomerase II alpha antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the Topoisomerase II alpha antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- Topoisomerase II alpha (TOP2A) (Topoisomerase (DNA) II alpha 170kDa (TOP2A))
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Andere Bezeichnung
- Topoisomerase II alpha
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Hintergrund
- The topoisomerase II-Alpha isoform is a 170 kDa nuclear protein and plays an important role in DNA synthesis and RNA transcription, as well as chromosomal segregation during mitosis. Topoisomerase II-Alpha is reported to be a sensitive and specific marker of late S-, G2- & M-phases in transformed and developmentally regulated normal cells, and has been shown to be over-expressed in many human cancers. Decreased expression of Topoisomerase II-Alpha is the predominant mechanism of resistance to several chemotherapeutic agents.
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UniProt
- P11388
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Pathways
- Zellzyklus, Mitotic G1-G1/S Phases
Target
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