TRAF1 Antikörper (AA 14-404)

Produktnummer ABIN7870634

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch TRAF1 in WB, ELISA und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für TRAF1 Antikörper (AA 14-404) (ABIN7870634)

Target: TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRAF1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-TRAF1 Antikörper

Bindungsspezifität: AA 14-404

Verwendungszweck: TRAF1 Antibody

Aufreinigung: Affinity purified

Immunogen: Recombinant human protein (amino acids D14-D404) was used as the immunogen for the TRAF1 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the TRAF1 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the TRAF1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu TRAF1

Target: TRAF1 (TNF Receptor-Associated Factor 1 (TRAF1))

Andere Bezeichnung: TRAF1

Hintergrund: TRAF1 (TNF Receptor-Associated Factor 1), also called EBI6, is a protein that in humans is encoded by the TRAF1 gene. The protein encoded by this gene is a member of the TNF receptor (TNFR) associated factor (TRAF) protein family. Siemienski et al.(1997) used fluorescence in situ hybridization to map the TRAF1 gene to 9q33-q34. Mosialos et al.(1995) found that LMP1, the EBV-transforming protein, specifically associates with LAP1 (TRAF3) or EBI6 in B lymphoblasts. LMP1 expression redirects LAP1 and EBI6 from scattered cytoplasmic structures to LMP1 plasma membrane patches. Both LAP1 and EBI6 associated with the cytoplasmic domain of p80/TNFR2 in vivo.

UniProt: Q13077

Pathways: NF-kappaB Signalweg, Apoptose, Cell-Cell Junction Organization, Asymmetric Protein Localization