Der Kaninchen Polyklonal anti-Choline Acetyltransferase Antikörper (ABIN7870510) detektiert spezifisch Choline Acetyltransferase in WB, ELISA und FACS.
Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.
CHAT
Reaktivität: Human
WB, IF, ICC
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Optimal dilution of the Choline Acetyltransferase antibody should be determined by the researcher.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Lyophilized
Buffer
0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
After reconstitution, the Choline Acetyltransferase antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
Choline acetyltransferase (commonly abbreviated as ChAT, but sometimes CAT) is a transferase enzyme responsible for the synthesis of the neurotransmitter acetylcholine. In humans, the choline acetyltransferase enzyme is encoded by the CHAT gene. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.