Choline Acetyltransferase Antikörper (AA 331-630)

Produktnummer ABIN3016135

Der Kaninchen Polyklonal anti-Choline Acetyltransferase Antikörper (ABIN3016135) detektiert spezifisch Choline Acetyltransferase in WB und IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Choline Acetyltransferase Antikörper (AA 331-630) (ABIN3016135)

Target: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Choline Acetyltransferase Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Produktdetails anti-Choline Acetyltransferase Antikörper

Bindungsspezifität: AA 331-630

Sequenz: VLVQCTEHLL KHMTQSSRKL IRADSVSELP APRRLRWKCS PEIQGHLASS AEKLQRIVKN LDFIVYKFDN YGKTFIKKQK CSPDAFIQVA LQLAFYRLHR RLVPTYESAS IRRFQEGRVD NIRSATPEAL AFVRAVTDHK AAVPASEKLL LLKDAIRAQT AYTVMAITGM AIDNHLLALR ELARAMCKEL PEMFMDETYL MSNRFVLSTS QVPTTTEMFC CYGPVVPNGY GACYNPQPET ILFCISSFHS CKETSSSKFA KAVEESLIDM RDLCSLLPPT ESKPLATKEK ATRPSQGHQP

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: Polyclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 331-630 of human CHAT (NP_001136401.1).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Choline Acetyltransferase

Target: Choline Acetyltransferase (CHAT) (Choline O-Acetyltransferase (CHAT))

Andere Bezeichnung: CHAT

Hintergrund: This gene encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. This gene product is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in this gene have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in this gene are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for this gene, and some of these variants have been shown to encode more than one isoform.,CHAT,CHOACTASE,CMS1A,CMS1A2,CMS6,Neuroscience,Cell Type Marker,Neuron marker,CHAT

Molekulargewicht: 70 kDa/74 kDa/82 kDa

Gen-ID: 1103

UniProt: P28329

Pathways: Skeletal Muscle Fiber Development