FANCA Antikörper (AA 1272-1439)

Produktnummer ABIN7870404

Der Kaninchen Polyklonal anti-FANCA Antikörper wird verwendet zum Nachweis von FANCA in Proben von Ratte und Maus. Er wurde validiert für WB, ELISA und FACS.

Kurzübersicht für FANCA Antikörper (AA 1272-1439) (ABIN7870404)

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FANCA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Produktdetails anti-FANCA Antikörper

Bindungsspezifität: AA 1272-1439

Verwendungszweck: Fanca Antibody / Fanconi anemia group A protein / FAA

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant mouse protein (amino acids E1272-F1439) was used as the immunogen for the Fanca antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Fanca antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the Fanca antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu FANCA

Target: FANCA (Fanconi Anemia Group A Protein (FANCA))

Andere Bezeichnung: Fanca

Hintergrund: Fanconi anaemia, complementation group A, also known as FAA, FACA and FANCA, is a protein which in humans is encoded by the FANCA gene. Acts upstream of or within several processes, including gonad development, regulation of CD40 signaling pathway, and regulation of regulatory T cell differentiation. Predicted to be located in nucleoplasm. Predicted to be part of Fanconi anaemia nuclear complex. Is expressed in several structures, including gut, liver, lung, reproductive system, and spleen. Used to study Fanconi anemia complementation group A. Human ortholog(s) of this gene implicated in several diseases, including Fanconi anemia (multiple), acute myeloid leukemia, esophagus squamous cell carcinoma, ovarian disease (multiple), and skin melanoma. Orthologous to human FANCA (FA complementation group A).

UniProt: Q9JL70

Pathways: DNA Reparatur