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FANCA Antikörper (Fanconi Anemia Group A Protein) AA 995-1009 Primary Antibody

FANCA Reaktivität: Human ELISA, WB Wirt: Kaninchen Polyclonal unconjugated
Pubmed (1 reference)
Produktnummer ABIN129606
$658.50
Zzgl. Versandkosten $45.00 und $20.00 Trockeneis
100 μg
local_shipping Lieferung nach: Vereinigte Staaten von Amerika
Lieferung in 1 bis 2 Werktagen
  • Target Alle FANCA Antikörper anzeigen
    FANCA
    Bindungsspezifität
    • 15
    • 13
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 995-1009
    Reaktivität
    • 68
    • 18
    • 11
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 78
    • 5
    Kaninchen
    Klonalität
    • 80
    • 3
    Polyklonal
    Konjugat
    • 39
    • 6
    • 5
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser FANCA Antikörper ist unkonjugiert
    Applikation
    • 47
    • 35
    • 15
    • 15
    • 15
    • 13
    • 13
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    ELISA, Western Blotting (WB)
    Kreuzreaktivität
    Schimpanse
    Produktmerkmale
    Concentration Definition: by UV absorbance at 280 nm
    Immunogen
    This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 995-1009 of human FANCA protein.
    Isotyp
    IgG
  • Applikationshinweise
    This affinity purified antibody has been tested for use in ELISA and by western blot.  Specific conditions for reactivity should be optimized by the end user. Expect a main band at approximately 163 kDa in size corresponding to FANCA by western blotting in the appropriate cell lysate or extract or human tissue.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    2.2 mg/mL
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Smogorzewska, Matsuoka, Vinciguerra, McDonald, Hurov, Luo, Ballif, Gygi, Hofmann, DAndrea, Elledge: "Identification of the FANCI protein, a monoubiquitinated FANCD2 paralog required for DNA repair." in: Cell, Vol. 129, Issue 2, pp. 289-301, (2007) (PubMed).

  • Target
    FANCA
    Andere Bezeichnung
    FANCA (FANCA Produkte)
    Synonyme
    FA, FA-H, FA1, FAA, FACA, FAH, FANCH, AW208693, Fanconi anemia complementation group A, Fanconi anemia, complementation group A, FANCA, Fanca
    Hintergrund
    FANCA (also called Protein FACA or Fanconi anemia group A protein) is involved in DNA repair, perhaps specifically with post-replication repair or a cell cycle checkpoint function. FANCA may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.  The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, and FANCL. The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia
    Synonyms: FA 1 antibody, FA antibody, FA H antibody, FA1 antibody, FAA antibody, FACA antibody, FAH antibody, FANCH antibody
    Gen-ID
    2175, 66880553
    UniProt
    O15360
    Pathways
    DNA Reparatur
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