MUC13 Antikörper (AA 100-300)

Produktnummer ABIN7869844

Der Maus Monoklonal anti-MUC13 Antikörper (Klon MUC13-13113) (ABIN7869844) detektiert spezifisch MUC13 in IHC (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MUC13 Antikörper (AA 100-300) (ABIN7869844)

Target: MUC13 (Mucin 13, Cell Surface Associated (MUC13))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MUC13 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Güteklasse: Carrier-free

Klon: MUC13-13113

Produktdetails anti-MUC13 Antikörper

Bindungsspezifität: AA 100-300

Verwendungszweck: Mucin 13 Antibody / MUC13 (azide and preservative free)

Aufreinigung: Protein A affinity

Immunogen: A portion of amino acids 100-300 from human Mucin 13 protein was used as the immunogen for the Mucin 13 antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the Mucin 13 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Konservierungsmittel: Azide free

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the Mucin 13 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu MUC13

Target: MUC13 (Mucin 13, Cell Surface Associated (MUC13))

Andere Bezeichnung: Mucin 13

Hintergrund: Mucins are epithelial glycoproteins with a high content of clustered oligosaccharides that are O-glycoside linked to tandem repeat peptides rich in threonine, serine and proline. Mucin 13 (MUC13), also designated downregulated in colon cancer 1 (DRCC1), is an epithelial and hemopoietic type I membrane protein that undergoes secretion and influences gastrointestinal mucosa levels. It is most abundant in epithelial tissues of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach. Mucin 13 is a good differentiation marker for gastrointestinal mucosa and may also indicate certain gastric tumors. It localizes to the apical membrane of both columnar and goblet cells in the gastrointestinal tract, and within goblet cell thecae. Mucin 13 is a cleaved protein, and the b subunit, containing the cytoplasmic tail, can homodimerize.

UniProt: Q9H3R2