MUC13 Antikörper (AA 100-300)

Produktnummer ABIN7865388

Der Maus Monoklonal anti-MUC13 Antikörper (Klon MUC13-13113) (ABIN7865388) detektiert spezifisch MUC13 in IHC. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für MUC13 Antikörper (AA 100-300) (ABIN7865388)

Target: MUC13 (Mucin 13, Cell Surface Associated (MUC13))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MUC13 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC)

Klon: MUC13-13113

Produktdetails anti-MUC13 Antikörper

Bindungsspezifität: AA 100-300

Verwendungszweck: MUC13 / Mucin 13 Antibody

Spezifität: Mucins are epithelial glycoproteins with a high content of clustered oligosaccharides that are O-glycoside linked to tandem repeat peptides rich in threonine, serine and proline. Mucin 13 (MUC13), also designated downregulated in colon cancer 1 (DRCC1), is an epithelial and hemopoietic type I membrane protein that undergoes secretion and influences gastrointestinal mucosa levels. It is most abundant in epithelial tissues of the gastrointestinal and respiratory tracts, such as large intestine and trachea, followed by kidney, small intestine, appendix and stomach. Mucin 13 is a good differentiation marker for gastrointestinal mucosa and may also indicate certain gastric tumors. It localizes to the apical membrane of both columnar and goblet cells in the gastrointestinal tract, and within goblet cell thecae. Mucin 13 is a cleaved protein, and the b subunit, containing the cytoplasmic tail, can homodimerize.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment (around aa100-300) of human MUC13 protein (exact sequence is proprietary)

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu MUC13

Target: MUC13 (Mucin 13, Cell Surface Associated (MUC13))

Andere Bezeichnung: MUC13

Hintergrund:

DRCC1, MUC-13

Human colon or small intestine.

Molekulargewicht: 58kDa

Gen-ID: 56667, 514227

UniProt: Q9H3R2