Aurora A Antikörper (AA 1-395)
Kurzübersicht für Aurora A Antikörper (AA 1-395) (ABIN7869297)
Target
Alle Aurora A (AURKA) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-395
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Verwendungszweck
- Ark-1 Antibody / Aurora-related kinase 1 / Aurka
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Aufreinigung
- Antigen affinity purified
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Immunogen
- Recombinant mouse protein (amino acids M1-S395) was used as the immunogen for the Ark-1 antibody.
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Isotyp
- IgG
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Applikationshinweise
- Optimal dilution of the Ark-1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- After reconstitution, the Ark-1 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.
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- Aurora A (AURKA) (Aurora Kinase A (AURKA))
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Andere Bezeichnung
- Ark-1
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Hintergrund
- AURKA (Aurora kinase A), also called ARK-1 (Aurora-related kinase 1), AurA, AIK, AURORA2, BTAK, PPP1R47, STK7, STK15, and STK6 is a mitotic centrosomal protein kinase. The main role of AURKA/ARK-1 in tumor development is in controlling chromosome segregation during mitosis. Aurora A / Aurora-related kinase 1 is a member of a family of mitotic serine/threonine kinases. The AURKA gene is overexpressed in many human cancers. Ectopic overexpression in mammalian cells induces centrosome amplification, chromosome instability, and oncogenic transformation, a phenotype characteristic of loss-of-function mutations of p53.
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UniProt
- P97477
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Pathways
- Zellzyklus, Asymmetric Protein Localization
Target
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