FGF23 Antikörper (AA 1-251)

Produktnummer ABIN7868975

Dieser Maus Monoklonal Antikörper detektiert spezifisch FGF23 in IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für FGF23 Antikörper (AA 1-251) (ABIN7868975)

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser FGF23 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: FGF23-6372

Produktdetails anti-FGF23 Antikörper

Bindungsspezifität: AA 1-251

Verwendungszweck: FGF23 Antibody / Fibroblast Growth Factor 23

Aufreinigung: Protein A/G affinity

Immunogen: A recombinant partial protein sequence (within amino acids 1-251) from the human protein was used as the immunogen for the FGF23 antibody.

Isotyp: IgG2b, kappa

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the FGF23 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Aliquot the FGF23 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Details zu FGF23

Target: FGF23 (Fibroblast Growth Factor 23 (FGF23))

Andere Bezeichnung: FGF23

Hintergrund: Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the FGF family include the oncogenes FGF-3 (Int2) and FGF-4 (hst/Kaposi), FGF-5, FGF-6, FGF-7 (KGF), FGF-8 (AIGF), FGF-9 (GAF) and FGF-10 through FGF-23. Members of the FGF family share 30-55 % amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in transfected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

UniProt: Q9GZV9

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Negative Regulation of Hormone Secretion