NLRP7 Antikörper (AA 1-169)

Produktnummer ABIN7868239

Der Kaninchen Polyklonal anti-NLRP7 Antikörper (ABIN7868239) detektiert spezifisch NLRP7 in ELISA, WB, IHC (p) und FACS. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für NLRP7 Antikörper (AA 1-169) (ABIN7868239)

Target: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NLRP7 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Produktdetails anti-NLRP7 Antikörper

Bindungsspezifität: AA 1-169

Verwendungszweck: NLRP7 Antibody

Aufreinigung: Antigen affinity purified

Immunogen: Recombinant human protein (amino acids M1-L169) was used as the immunogen for the NLRP7 antibody.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal dilution of the NLRP7 antibody should be determined by the researcher.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: After reconstitution, the NLRP7 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Details zu NLRP7

Target: NLRP7 (NLR Family, Pyrin Domain Containing 7 (NLRP7))

Andere Bezeichnung: NLRP7

Hintergrund: NACHT, LRR and PYD domains-containing protein 7 is a protein that in humans is encoded by the NLRP7 gene. This gene encodes a member of the NACHT, leucine rich repeat, and PYD containing (NLRP) protein family. It has an N-terminal pyrin domain, followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. NLRP proteins are implicated in the activation of proinflammatory caspases through multiprotein complexes called inflammasomes. This gene may act as a feedback regulator of caspase-1-dependent interleukin 1-beta secretion. Alternative splicing results in multiple transcript variants encoding different isoforms.

UniProt: Q8WX94

Pathways: Inflammasome