JAZF1 Antikörper (AA 1-130)
Kurzübersicht für JAZF1 Antikörper (AA 1-130) (ABIN7868080)
Target
Alle JAZF1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 1-130
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Verwendungszweck
- JAZF1 Antibody
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Aufreinigung
- Protein A/G affinity
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Immunogen
- A portion of amino acids 1-130 was used as the immunogen for the JAZF1 antibody.
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Isotyp
- IgG2a
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Applikationshinweise
- Optimal dilution of the JAZF1 antibody should be determined by the researcher.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 mg/mL
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Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Aliquot the JAZF1 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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- JAZF1 (JAZF Zinc Finger 1 (JAZF1))
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Andere Bezeichnung
- JAZF1
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Hintergrund
- JAZF1 (juxtaposed with another zinc finger protein 1), also known as TIP27 (TAK1-interacting protein 27) or ZNF802 (zinc finger protein 802), is a 243 amino acid protein that localizes to the nucleus and contains three C2H2-type zinc fingers. Existing as multiple alternatively spliced isoforms, JAZF1 interacts with the nuclear orphan receptor TR4 and is thought to function as a transcriptional repressor, effectively down-regulation the expression of TR4. Chromosomal aberrations in the gene encoding JAZF1 are associated with the pathogenesis of endometrial stromal tumors, suggesting a role for JAZF1 in carcinogenesis.
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UniProt
- Q86VZ6
Target
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