Rekombinanter HBEGF Antikörper (PE)
Kurzübersicht für Rekombinanter HBEGF Antikörper (PE) (ABIN7867302)
Target
Alle HBEGF Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- PE-conjugated Anti-HBEGF antibody(DMC500), IgG1 Chimeric mAb
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Aufreinigung
- Purified from cell culture supernatant by affinity chromatography
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Isotyp
- IgG1
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Applikationshinweise
- Flow Cyt 1:100
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- Liquid PBS with 0.05 % Proclin300, 1 % BSA
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- Store at 2°C-8°C for 6 months
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Haltbarkeit
- 6 months
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- HBEGF (Heparin-Binding EGF-Like Growth Factor (HBEGF))
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Andere Bezeichnung
- HBEGF
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Hintergrund
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Synonyms: DTR, DTS, DTSF, HEGFL
Target Background: Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor:EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB:Swiss-Prot Function]
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UniProt
- Q99075
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Pathways
- RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung
Target
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