Progesterone Receptor Antikörper
Kurzübersicht für Progesterone Receptor Antikörper (ABIN7865720)
Target
Alle Progesterone Receptor (PGR) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Verwendungszweck
- anti-Progesterone Receptor mouse monoclonal, PR-80, purified
-
Aufreinigung
- affinity chromatography
-
Immunogen
- recombinant human progesterone receptor protein
-
Isotyp
- IgG1 kappa
-
-
-
-
Applikationshinweise
-
IHC-paraffin_dilution: 1:25-1:50 (2-4 μg/mL, microwave treatment in 10 mM citrate buffer pH 6.0 recommended)
IHC-frozen_dilution: 1:25-1:50 (2-4 μg/mL)
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- 100 μg/mL
-
Buffer
- PBS with 0.02 % sodium azide
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C
-
Informationen zur Lagerung
- store at 2 - 8 °C
-
-
- Progesterone Receptor (PGR)
-
Andere Bezeichnung
- Progesterone Receptor
-
Hintergrund
- PR-80 is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81 kDa) and PR-B (116 kDa). Expression of PgR has been suggested to reflect an intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. Positive control: PR positive breast cancer, T47-D cells.
-
Pathways
- Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration
Target
-