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Progesterone Receptor Antikörper (AA 1-110)

Name: Progesterone Receptor Antikörper (AA 1-110)
SKU: ABIN562204
Price: 640.64 EUR
Availability: InStock

PGR Reaktivität: Human WB, ELISA, IHC (p), IF Wirt: Maus Monoclonal 5D10 unconjugated

Western Blot detection against Immunogen (37.

Immunofluorescence of monoclonal antibody to PGR on MCF-7 cell.

Detection limit for recombinant GST tagged PGR is approximately 0.

ELISA

Immunoperoxidase of monoclonal antibody to PGR on formalin-fixed paraffin-embedded human breast cancer.

IHC (fp)

ISt

5 Abbildungen

(2 Referenzen)

Produktnummer ABIN562204

Datenblatt (PDF)

Target Alle Progesterone Receptor (PGR) Antikörper anzeigen

Progesterone Receptor (PGR)
Bindungsspezifität
16

16

15

14

13

12

11

10

8

8

8

8

7

7

7

7

6

6

5

5

3

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 1-110
Reaktivität
238

42

38

16

15

8

6

6

5

3

3

2

1

1

1

1

1
Human
Wirt
182

58

1

1
Maus
Passende Sekundärantikörper
Klonalität
176

66
Monoklonal
Konjugat
119

21

11

11

8

7

7

7

7

7

7

7

2

2

2

2

2

2

2

2

2

2

2

1
Dieser Progesterone Receptor Antikörper ist unkonjugiert
Applikation
175

89

56

31

27

26

26

24

18

18

17

12

6

3

2

1

1

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Verwendungszweck

Mouse monoclonal antibody raised against a partial recombinant PGR. This PGR gene uses two distinct promoters and translation start sites in the first exon to produce two isoforms, A and B. The two isoforms are identical except for the additional 165 amino acids found in the N-terminus of isoform B. Our immunogen corresponds to the specific region of isoform B, thus this antibody is a PGR isofrom B specific antibody.

Sequenz

MTELKAKGPR APHVAGGPPS PEVGSPLLCR PAAGPFPGSQ TSDTLPEVSA IPISLDGLLF PRPCQGQDPS DEKTQDQQSL SDVEGAYSRA EATRGAGGSS SSPPEKDSGL

Kreuzreaktivität

Human, Ratte

Produktmerkmale

Antibody Reactive Against Recombinant Protein.

Immunogen

PGR (NP_000917, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Klon

5D10

Isotyp

IgG1

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Applikationshinweise

Optimal working dilution should be determined by the investigator.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Buffer

In 1x PBS, pH 7.4

Handhabung

Aliquot to avoid repeated freezing and thawing.

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Liu, Chang, Kuo, Hwa, Lin, Huang, Chen, Chang, Hsieh: "Major Functional Transcriptome of an Inferred Center Regulator of an ER(-) Breast Cancer Model System." in: Cancer informatics, Vol. 11, pp. 87-111, (2012) (PubMed).

Liu, Chang, Kuo, Hwa, Shyu, Chang, Hsieh: "In Silico Prediction for Regulation of Transcription Factors onTheir Shared Target Genes Indicates Relevant Clinical Implications in a Breast Cancer Population." in: Cancer informatics, Vol. 11, pp. 113-37, (2012) (PubMed).
Target

Progesterone Receptor (PGR)

Andere Bezeichnung

PGR (PGR Produkte)

Synonyme

NR3C3 antikoerper, PR antikoerper, 9930019P03Rik antikoerper, BB114106 antikoerper, ENSMUSG00000074510 antikoerper, PR-A antikoerper, PR-B antikoerper, XPR-1 antikoerper, pgr antikoerper, xpr-2 antikoerper, LOC443444 antikoerper, PGR antikoerper, pg antikoerper, pr antikoerper, gb:dq017620 antikoerper, progesterone receptor antikoerper, progesterone receptor L homeolog antikoerper, PGR antikoerper, Pgr antikoerper, pgr.L antikoerper, pgr antikoerper

Hintergrund

Full Gene Name: progesterone receptor
Synonyms: NR3C3,PR

Gen-ID

5241

NCBI Accession

NM_000926

Pathways

Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration