Integrin Alpha2b Antikörper
Kurzübersicht für Integrin Alpha2b Antikörper (ABIN7865660)
Target
Alle Integrin Alpha2b (CD41) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- anti-CD41a mouse monoclonal, 96-2C1, purified
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Aufreinigung
- affinity chromatography
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Immunogen
- stimulated human PBL
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Isotyp
- IgG1 kappa
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Applikationshinweise
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ICC/IF_dilution: 1:50-1:100 (1-2 μg/mL)
FACS_dilution: 1-2 μg/million cells
IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 100 μg/mL
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Buffer
- PBS with 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- store at 2 - 8 °C
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- Integrin Alpha2b (CD41)
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Andere Bezeichnung
- CD41a
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Hintergrund
- 96-2C1 reacts with a calcium-dependent complex of CD41/CD61 (GPIIb/IIIa, integrin IIa/3), a dimer of 90 and 140 kDa, present on the membrane of normal platelets and megakaryocytes. This complex forms the receptor of fibrinogen, fibronectin and Von Willebrand factor, and mediates platelet adhesion and aggregation. MAbs to CD41a have been shown to have anti-proliferative effects on various lymphoid cell lines, particularly those derived from large cell lymphomas. 96-2C1 was typed at the IIId HLDA workshop. Positive control: KG1a, HEL cells, and human platelets in lymph nodes or tonsils.
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Pathways
- Integrin Complex
Target
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