CD70 Antikörper

Produktnummer ABIN7865603

Dieser Maus Monoklonal Antikörper detektiert spezifisch CD70 in ELISA, IHC, FACS, IF, IP und ICC. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für CD70 Antikörper (ABIN7865603)

Target: CD70 (CD70 Molecule (CD70))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD70 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Klon: EBS-CD-039

Produktdetails anti-CD70 Antikörper

Verwendungszweck: anti-CD70 mouse monoclonal, EBS-CD-039, purified

Aufreinigung: affinity chromatography

Immunogen: human WM-1 (Waldenstrom's macroglobulinemia) cells

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise:

ICC/IF_dilution: 1:100-1:200 (0.5-1.0 μg/mL)

FACS_dilution: 0.5-1.0 μg/million cells in 0.1 ml

IHC-frozen_dilution: 1:50-1:100 (1-2 μg/mL)

elisa_dilution: assay dependent

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 100 μg/mL

Buffer: PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: store at 2 - 8 °C

Details zu CD70

Target: CD70 (CD70 Molecule (CD70))

Andere Bezeichnung: CD70

Hintergrund: CD70 is a 30 kDa cytokine that belongs to the tumor necrosis factor (TNF) ligand family. CD70 is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T- and b-lymphocytes. It induces proliferation of co-stimulated T-cells, enhaces the generation of cytolytic T-cells, and constributes to T-cell activation. It futher plays a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin synthesis. EBS-CD-039 blocks the interaction between CD27 and CD70, and has been shown to inhibit T-cell proliferation induced by dendritic cells. Positive control: Raji cells, lymph node or tonsil.

Pathways: Cancer Immune Checkpoints