Stathmin 1 Antikörper
Kurzübersicht für Stathmin 1 Antikörper (ABIN7862127)
Target
Alle Stathmin 1 (STMN1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Verwendungszweck
- Stathmin 1 / STMN1 Antibody
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Spezifität
- Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation.Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.
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Aufreinigung
- 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.
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Immunogen
- Recombinant fragment of human STMN1 protein (exact sequence is proprietary)
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Isotyp
- IgG2b, kappa
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Konzentration
- 1.0 mg/mL
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Buffer
- Prepared in 10 mM PBS
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Konservierungsmittel
- Azide free
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.
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- Stathmin 1 (STMN1)
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Andere Bezeichnung
- Stathmin 1
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Hintergrund
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C1orf215, Lag, LAP18, Leukemia associated phosphoprotein p18, Metablastin, Oncoprotein 18, Op18, Phosphoprotein 19, Phosphoprotein p19, pp17, pp19, Pr22 protein, Prosolin, Protein Pr22, SMN, Stathmin1, STMN 1
Human brain or melanoma tissue.
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Molekulargewicht
- 19kDa
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Gen-ID
- 3925, 209983
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UniProt
- P16949
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Pathways
- MAPK Signalweg, Microtubule Dynamics
Target
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