Rekombinanter Stathmin 1 Antikörper

Produktnummer ABIN7864320

Der Kaninchen Monoklonal anti-Stathmin 1 Antikörper wird verwendet zum Nachweis von Stathmin 1 in Proben von Human. Er wurde validiert für WB und IHC.

Kurzübersicht für Rekombinanter Stathmin 1 Antikörper (ABIN7864320)

Target: Stathmin 1 (STMN1)

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Stathmin 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Klon: STMN1-8023R

Produktdetails anti-Stathmin 1 Antikörper

Verwendungszweck: Recombinant Stathmin 1 / STMN1 Antibody

Spezifität: Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed, and it is expressed as two different isoforms. Op18 is considered a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein, via phophorylation, for a variety of cell signaling pathways and is involved in both mitosis and differentiation.Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant fragment of human STMN1 protein (exact sequence is proprietary)

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C.Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Details zu Stathmin 1

Target: Stathmin 1 (STMN1)

Andere Bezeichnung: Stathmin 1

Hintergrund:

C1orf215, Lag, LAP18, Leukemia associated phosphoprotein p18, Metablastin, Oncoprotein 18, Op18, Phosphoprotein 19, Phosphoprotein p19, pp17, pp19, Pr22 protein, Prosolin, Protein Pr22, SMN, Stathmin1, STMN 1

Human brain or melanoma tissue. A431, Jurkat, PC3.

Molekulargewicht: 19kDa

Gen-ID: 3925, 209983

UniProt: P16949

Pathways: MAPK Signalweg, Microtubule Dynamics