LMYC Antikörper

Produktnummer ABIN7863177

Dieser Maus Monoklonal Antikörper detektiert spezifisch LMYC in WB, ELISA, IF und FACS. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für LMYC Antikörper (ABIN7863177)

Target: LMYC (MYCL) (Protein L-Myc (MYCL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LMYC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

Klon: PCRP-MYCL-2D5

Produktdetails anti-LMYC Antikörper

Verwendungszweck: L-Myc / MYCL1 (Transcription Factor) Antibody

Spezifität: Oncogene-encoded proteins c-Myc, N-Myc, and L-Myc function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors, the N-Myc gene in neuroblastomas, and the L-Myc gene in human small cell lung carcinomas. c-Myc protein is a transcription factor localized to the nucleus of the cell. It seems to be involved in activating the transcription of growth-related genes. c-Myc binds to DNA during transcription as a heterodimeric complex with Max. c-Myc is phosphorylated in vitro by p44/42 MAP kinase at Ser62 and in vivo at both Thr58 and Ser62. Mutation of Thr58 and Ser62 to Ala inhibits the ability of c-Myc to activate transcription.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human MYCL protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu LMYC

Target: LMYC (MYCL) (Protein L-Myc (MYCL))

Andere Bezeichnung: L-Myc

Hintergrund:

bHLHe38, Class E basic helix-loop-helix protein 38, l myc 1 proto-oncogene, Myc related gene from lung cancer, oncogene lmyc, Protein L-Myc-1, v myc avian myelocytomatosis viral oncogene homolog 1 lung carcinoma derived

HeLa cells. Human small cell lung carcinoma.

Molekulargewicht: 40.33kDa

Gen-ID: 4610, 437922

UniProt: P12524

Pathways: Warburg Effekt