LMYC Antikörper

Produktnummer ABIN7126732

Produktdetails anti-LMYC Antikörper

Target: LMYC (MYCL) (Protein L-Myc (MYCL))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LMYC Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS), Coating (Coat)

Spezifität: Oncogene-encoded proteins c-Myc, N-Myc, and L-Myc function in cell proliferation, differentiation and neoplastic disease. Amplification of the c-Myc gene has been found in several types of human tumors, the N-Myc gene in neuroblastomas, and the L-Myc gene in human small cell lung carcinomas. c-Myc protein is a transcription factor localized to the nucleus of the cell. It seems to be involved in activating the transcription of growth-related genes. c-Myc binds to DNA during transcription as a heterodimeric complex with Max. c-Myc is phosphorylated in vitro by p44/42 MAP kinase at Ser62 and in vivo at both Thr58 and Ser62. Mutation of Thr58 and Ser62 to Ala inhibits the ability of c-Myc to activate transcription.

Kreuzreaktivität (Details): Human.

Aufreinigung: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant full-length human MYCL protein

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

Known_Application: ELISA (For coating, order antibody without BSA), ,Immunoprecipitation (1-2 μg per 100-500 μg of total protein (1 mL of cell lysate)), ,Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Western Blot (1-2 μg/mL), ,Optimal dilution for a specific application should be determined.

Positive_Control: HeLa cells. Human small cell lung carcinoma.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Konservierungsmittel: Azide free

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Haltbarkeit: 24 months

Details zu LMYC

Target: LMYC (MYCL) (Protein L-Myc (MYCL))

Andere Bezeichnung: MYCL (MYCL Produkte)

Synonyme: MRTL antikoerper, MYCC antikoerper, bHLHe39 antikoerper, c-Myc antikoerper, MYCL1 antikoerper, Lmyc1 antikoerper, Mycl1 antikoerper, LMYC antikoerper, bHLHe38 antikoerper, CMYC antikoerper, c-myc antikoerper, ARC antikoerper, B430311C09Rik antikoerper, MYC antikoerper, NOP antikoerper, Nop30 antikoerper, RNCMYC antikoerper, mMyc antikoerper, C-MYC antikoerper, AU016757 antikoerper, Myc2 antikoerper, Niard antikoerper, Nird antikoerper, AW536278 antikoerper, L-myc antikoerper, Lmyc-1 antikoerper, l-myc antikoerper, lmyc antikoerper, lmyc-b antikoerper, lmyc2 antikoerper, mycl1-b antikoerper, xL-Myc2 antikoerper, fi04c04 antikoerper, mycl1b antikoerper, si:ch211-194e15.2 antikoerper, wu:fa07c04 antikoerper, wu:fb19f03 antikoerper, wu:fi04c04 antikoerper, zgc:152988 antikoerper, lmyc1 antikoerper, mycl1 antikoerper, mycl1a antikoerper, zgc:85967 antikoerper, lmyc-A antikoerper, mycl antikoerper, mycl1-a antikoerper, xL-Myc1 antikoerper, xL-myc1 antikoerper, MYC proto-oncogene, bHLH transcription factor antikoerper, v-myc avian myelocytomatosis viral oncogene lung carcinoma derived homolog antikoerper, MYCL proto-oncogene, bHLH transcription factor antikoerper, nucleolar protein 3 (apoptosis repressor with CARD domain) antikoerper, myelocytomatosis oncogene antikoerper, v-myc avian myelocytomatosis viral oncogene lung carcinoma derived antikoerper, MYCL proto-oncogene, bHLH transcription factor S homeolog antikoerper, MYCL proto-oncogene, bHLH transcription factor b antikoerper, MYCL proto-oncogene, bHLH transcription factor a antikoerper, MYCL proto-oncogene, bHLH transcription factor L homeolog antikoerper, MYC antikoerper, MYCL antikoerper, Mycl antikoerper, Nol3 antikoerper, Myc antikoerper, mycl.S antikoerper, myclb antikoerper, mycla antikoerper, mycl.L antikoerper

Hintergrund: BHLHe38, Class E basic helix-loop-helix protein 38, l myc 1 proto-oncogene, Myc related gene from lung cancer, oncogene lmyc, Protein L-Myc-1, v myc avian myelocytomatosis viral oncogene homolog 1 lung carcinoma derived,L-Myc / MYCL1 (Transcription Factor)
Cellular localisation: Nucleus. Nucleoplasm. Mitotic chromosome.

Molekulargewicht: 40.33kDa

Gen-ID: 4610, 437922

UniProt: P12524

Pathways: Warburg Effekt