Rekombinanter PMEPA1 Antikörper

Produktnummer ABIN7863299

Der Kaninchen Monoklonal anti-PMEPA1 Antikörper (Klon PMEPA1-6421R) (ABIN7863299) detektiert spezifisch PMEPA1 in IHC und WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für Rekombinanter PMEPA1 Antikörper (ABIN7863299)

Target: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Antikörpertyp: Recombinant Antibody

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser PMEPA1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Klon: PMEPA1-6421R

Produktdetails anti-PMEPA1 Antikörper

Verwendungszweck: Recombinant PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein) Antibody

Spezifität: PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.

Aufreinigung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G.

Immunogen: Recombinant full-length human PMEPA1 protein

Isotyp: IgG, kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 200 μg/mL

Buffer: Prepared in 10 mM PBS with 0.05 % BSA & 0.05 % azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Antibody with azide - store at 2 to 8 °C. Antibody without azide - store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.

Haltbarkeit: 24 months

Details zu PMEPA1

Target: PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))

Andere Bezeichnung: PMEPA1

Hintergrund:

PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA

Human prostate, breast or renal cell carcinoma tissue (IHC).

Molekulargewicht: 32kDa

Gen-ID: 56937, 517155

UniProt: Q969W9

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway