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PMEPA1 Antikörper

PMEPA1 Reaktivität: Human IHC (f) Wirt: Maus Monoclonal PMEPA1-2697 unconjugated
Produktnummer ABIN6938199
  • Target Alle PMEPA1 Antikörper anzeigen
    PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
    Reaktivität
    • 19
    • 3
    • 2
    Human
    Wirt
    • 13
    • 6
    Maus
    Klonalität
    • 12
    • 7
    Monoklonal
    Konjugat
    • 17
    • 1
    • 1
    Dieser PMEPA1 Antikörper ist unkonjugiert
    Applikation
    • 13
    • 11
    • 8
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Spezifität
    PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.
    Kreuzreaktivität (Details)
    Human.
    Aufreinigung
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant full-length human PMEPA1 protein
    Klon
    PMEPA1-2697
    Isotyp
    IgG kappa
    Top Product
    Discover our top product PMEPA1 Primärantikörper
  • Applikationshinweise

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: SKBR-3 cells. Prostate, Breast or Renal Cell Carcinoma.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Konservierungsmittel
    Azide free
    Lagerung
    -20 °C,-80 °C
    Informationen zur Lagerung
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Haltbarkeit
    24 months
  • Target
    PMEPA1 (Prostate Transmembrane Protein, Androgen Induced 1 (PMEPA1))
    Andere Bezeichnung
    PMEPA1 (PMEPA1 Produkte)
    Synonyme
    Tmepai antikoerper, PMEPA1 antikoerper, TMEPAI antikoerper, zgc:92731 antikoerper, tmepai antikoerper, STAG1 antikoerper, 2210418I02Rik antikoerper, AW455466 antikoerper, Erg1.2 antikoerper, N4wbp4 antikoerper, Stag1 antikoerper, prostate transmembrane protein, androgen induced 1 antikoerper, prostate transmembrane protein, androgen induced 1 L homeolog antikoerper, Pmepa1 antikoerper, PMEPA1 antikoerper, pmepa1 antikoerper, pmepa1.L antikoerper
    Hintergrund
    PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA,PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein)
    Cellular localisation: Cell Surface and Cytoplasmic
    Molekulargewicht
    32kDa
    Gen-ID
    56937, 517155
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway
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